All AbMole products are for research use only, cannot be used for human consumption.
WIN 18446 is a inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2) (IC50 = 0.3 μM). Inhibits the biosynthesis of retinoic acid from retinol in neonatal and adult murine testis.
Adv Sci (Weinh). 2025 Sep 03; .
Stage‐Resolved Phosphoproteomic Landscape of Mouse Spermiogenesis Reveals Key Kinase Signaling in Sperm Morphogenesis
WIN 18446 purchased from AbMole
| Molecular Weight | 366.11 |
| Formula | C12H20Cl4N2O2 |
| CAS Number | 1477-57-2 |
| Solubility (25°C) | DMSO 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related ALDH Products |
|---|
| CVT-10216
CVT-10216 is a highly selective, reversible inhibitor of ALDH-2 that reduces excessive alcohol drinking. |
| 4-Diethylaminobenzaldehyde
4-Diethylaminobenzaldehyde |
| Alda-1
Alda-1 is a potent and selective Aldehyde Dehydrogenase-2 Agonist. Alda-1 activates wild-type ALDH2 and restores near wild-type activity to ALDH2*2. |
| NCT-501
NCT-501 is a potent and selective inhibitor of Aldehyde dehydrogenase ALDH1A1, a dehydrogenase that has been found to be elevated in certain cancers and in cancer stem cells. |
| 4-Hydroxynonenal
4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
