All AbMole products are for research use only, cannot be used for human consumption.
Vancomycin hydrochloride (Vancocin) is a hydrochloride of vancomycin that is a narrow-spectrum glycopeptide antibacterial agent. Vancomycin acts by inhibiting proper cell wall synthesis in Gram-positive bacteria. Due to the different mechanism by which Gram-negative bacteria produce their cell walls and the various factors related to entering the outer membrane of Gram-negative organisms, vancomycin is not active against Gram-negative bacteria (except some non-gonococcal species of Neisseria).
ACS Nano. 2023 Mar 30.
Bioinspired Mild Photothermal Effect-Reinforced Multifunctional Fiber Scaffolds Promote Bone Regeneration
Vancomycin HCl purchased from AbMole
Microbiol Res. 2022 Aug;261:127047.
Interaction between gut microbiota dysbiosis and lung infection as gut-lung axis caused by Streptococcus suis in mouse model
Vancomycin HCl purchased from AbMole
| Cell Experiment | |
|---|---|
| Cell lines | Vero cells |
| Preparation method | Cells were seeded in each well of 24 well-plates and incubated under the same conditions and divided into three major groups in triplicates. One control group Cn was left untreated while group DMSO was treated with 0.1% DMSO. Vancomycin treated groups were divided into V1 (0.6 mg/mL), V2 (3.0 mg/mL), and V3 (6.0 mg/mL) to find out the cytotoxic effect of the antibiotic after 24hrs of vancomycin treatment. |
| Concentrations | 0.6 mg/mL - 6 mg/mL |
| Incubation time | 24 h |
| Animal Experiment | |
|---|---|
| Animal models | BALB/c male mice |
| Formulation | dd H2O |
| Dosages | 0.5 g/L dissolved in drinking water |
| Administration | Oral |
| Molecular Weight | 1485.71 |
| Formula | C66H75Cl2N9O24.HCl |
| CAS Number | 1404-93-9 |
| Solubility (25°C) | Water ≥ 50 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Alaina N Burns, et al. A Moving Target-Vancomycin Therapeutic Monitoring
[2] Donald P Levine. Vancomycin: a history
[3] Michael J Rybak. The pharmacokinetic and pharmacodynamic properties of vancomycin
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|---|
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| Linezolid
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| Daptomycin
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| Sulfadimethoxine
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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