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Tiragolumab

Cat. No. M24851

All AbMole products are for research use only, cannot be used for human consumption.

Tiragolumab Structure
Size Price Availability Quantity
100ug USD 150  USD150 In stock
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Quality Control & Documentation
Biological Activity

Tiragolumab is an immune checkpoint inhibitor that binds to T-cell immunoglobulin and the structural domain of ITIM (TIGIT), targeting TIGIT with an intact Fc region.TIGIT is a novel inhibitory immune checkpoint expressed primarily on the surface of T-cells and natural killer (NK) cells, which suppresses an organism's immune response to cancer. It can be used in studies related to solid tumors.

Chemical Information
CAS Number 1918185-84-8
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Danielle Brazel, et al. Lung Cancer (Auckl). Tiragolumab (Anti-TIGIT) in SCLC: Skyscraper-02, a Towering Inferno

[2] No authors listed. Cancer Discov. Tiragolumab Results Cast Shadow on TIGIT Pipeline

[3] Peter Sidaway. Nat Rev Clin Oncol. Tiragolumab active in PD-L1+ NSCLC

[4] Byoung Chul Cho, et al. Lancet Oncol. Tiragolumab plus atezolizumab versus placebo plus atezolizumab as a first-line treatment for PD-L1-selected non-small-cell lung cancer (CITYSCAPE): primary and follow-up analyses of a randomised, double-blind, phase 2 study

Related TIGIT Products
Domvanalimab

Domvanalimab (AB154) is an anti-TIGIT humanized monoclonal antibody. Domvanalimab binds human TIGIT9 and blocks the TIGIT-CD155 interaction. Domvanalimab can be used in research of cancer.

  Catalog
Abmole Inhibitor Catalog




Keywords: Tiragolumab supplier, TIGIT, inhibitors, activators

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