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TGF-beta RI Kinase Inhibitor VII is a selective TGF-β inhibitor. TGF-beta RI Kinase Inhibitor VII can effectively inhibit the TGF-β signaling pathway. TGF-beta RI Kinase Inhibitor VII has IC50 values of 13 μM and 0.63 μM for c-Src kinase and ALK5 kinase, respectively.
| Molecular Weight | 351.40 |
| Formula | C21H21NO4 |
| CAS Number | 666729-57-3 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related TGF-β Receptor Products |
|---|
| LY2157299
LY2157299 (Galunisertib) is a novel clinically relevant TBRI (ALK5 kinase) inhibitor with IC50 of 56 nM. |
| GW788388
GW788388 is a potent selective inhibitor of TGF-beta type I receptor and ALK5 with IC50 values of 0.093 and 0.018 μM. |
| LY364947
LY364947 is a selective small molecule inhibitor of the TGFβ type I receptor kinase with IC50 of 59 nM. |
| LY2109761
LY2109761 is a novel TGF-β receptor type I and type II dual inhibitor, with Ki values of 38 nM and 300 nM, respectively. |
| SB-525334
SB-525334 is a potent activin receptor-like kinase (ALK5)/ type I TGFβ-receptor kinase inhibitor with IC50 of 14.3 nM. |
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Products are for research use only. Not for human use. We do not sell to patients.
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