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Tesofensine (NS-2330) is a triple monoamine reuptake inhibitor inducing a potent inhibition of the re-uptake process in the synaptic cleft of the neurotransmitters dopamine (DA; IC50=6.5 nM), norepinephrine (NE;IC50=1.7 nM), and serotonin (5-HT;IC50=11 nM).
| Molecular Weight | 328.28 |
| Formula | C17H23Cl2NO |
| CAS Number | 195875-84-4 |
| Form | Solid |
| Solubility (25°C) | DMSO 2 mg/mL (ultrasonic and warming) |
| Storage | 4°C, protect from light |
[4] Agnès Sommet, et al. Lancet. Tesofensine and weight loss
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