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SLF1081851 is a Spns2 inhibitor, inhibits S1P release (IC50=1.93 μM). SLF1081851 plays a key role in development and immune system.
| Molecular Weight | 343.51 |
| Formula | C21H33N3O |
| CAS Number | 2763730-97-6 |
| Form | Solid |
| Solubility (25°C) | Ethanol 10 mg/mL (ultrasonic) |
| Storage | 4°C, protect from light |
| Related LPL Receptor Products |
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| Ki16425
Ki16425 is a LPA receptor antagonist with Ki values of 0.34, 6.5 and 0.93 μM for the human LPA1, LPA2 and LPA3 receptors, respectively. |
| Ki16198
Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively, shows weaker inhibition for LPA2, no activity at LPA4, LPA5, LPA6. |
| GSK-2018682
This compound belongs to the class of organic compounds known as n-alkylindoles. These are compounds containing an indole moiety that carries an alkyl chain at the 1-position. |
| H2L5186303
H2L5186303 is a potent and selective LPA2 receptor antagonist with an IC50 of 9 nM. |
| AM095 sodium
AM095 is a potent and selective, orally bioavailable antagonist of lysophosphatidic acid receptor1 (LPA1). |
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