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SBP-0636457 (SB1-0636457) is a SMAC mimetic, and as an IAP antagonist. SBP-0636457 binds to the BIR-domains of the IAP proteins, with a Ki of 0.27 μM. SBP-0636457 can be used for the research of solid tumors and hematologic cancers.
| Molecular Weight | 456.58 |
| Formula | C25H36N4O4 |
| CAS Number | 1422180-49-1 |
| Form | Solid |
| Solubility (25°C) | DMSO 45.71 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage | 4°C, sealed |
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