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RK-287107

Cat. No. M13713

All AbMole products are for research use only, cannot be used for human consumption.

RK-287107 Structure
Size Price Availability Quantity
5mg USD 240  USD240 In stock
10mg USD 360  USD360 In stock
50mg USD 1150  USD1150 In stock
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Quality Control & Documentation
Biological Activity

RK-287107 is a potent and specific tankyrase inhibitor with IC50s of 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively. RK-287107 blocks colorectal cancer cell growth.

Product Citations
Chemical Information
Molecular Weight 416.46
CAS Number 2171386-10-8
Solubility (25°C) DMSO 90 mg/mL
Storage 2-8°C, protect from light
References

[1] Fumiyuki Shirai, et al. J Med Chem. Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer

[2] Fumiyuki Shirai, et al. J Med Chem. Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors

[3] Anna Mizutani, et al. Cancer Sci. RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model

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