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Ritlecitinib tosylate is a first-in-class, orally active, dual covalent inhibitor of tyrosine kinases in the JAK3 and TEC families. The IC50 for JAK3 is 33.1 nM and there is no activity against JAK1, JAK2 and TYK2.
| Molecular Weight | 457.55 |
| Formula | C22H27N5O4S |
| CAS Number | 2192215-81-7 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] No authors listed. Am J Health Syst Pharm. Ritlecitinib Tosylate
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| Momelotinib (CYT387)
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