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PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a potent ferroptosis regulator glutathione peroxidase 4 (GPX4) allosteric activator (pEC50=4.7). PKUMDL-LC-101-D04 increases GPX4 activity to 150% at 20 μM in the cell-free assay and 61 μM in cell extracts.
| Molecular Weight | 378.94 |
| Formula | C14H23ClN4O2S2 |
| CAS Number | 2143896-83-5 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 120 mg/mL |
| Storage | -20°C, dry, sealed |
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