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Nystatin

Cat. No. M3290

All AbMole products are for research use only, cannot be used for human consumption.

Nystatin Structure
Synonym:

Fungicidin; Mycostatin

Size Price Availability Quantity
100mg USD 25  USD25 In stock
500mg USD 50  USD50 In stock
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Quality Control & Documentation
Biological Activity

Nystatin (Fungicidin) is a polyene antifungal antibiotic to which many molds and yeasts are sensitive, including Candida spp. Nystatin increases the permeability of plasma membranes to small monovalent ions, including chloridion. Nystatin increases apical chloridion permeability to the point where transepithelial chloridion transport is limited by transport across the basolateral membrane of tracheal epithelial cells, which reflects primarily the activity of the cotransporter. Nystatin (400 units/mL) increases the basal level of transepithelial 36Cl flux approximately 1.5-fold and eliminates UTP stimulation of this flux.

Nystatin combined with endostatin selectively enhances endostatin uptake and biodistribution in tumor blood vessels and tumor tissues but not in normal tissues of tumor-bearing mice, ultimately resulting in elevated antiangiogenic and antitumor efficacies of endostatin in vivo.

Product Citations
Chemical Information
Molecular Weight 926.09
Formula C47H75NO17
CAS Number 1400-61-9
Form Solid
Solubility (25°C) DMSO ≥ 30 mg/mL
Storage -20°C, protect from light, dry, sealed
References

[1] Xin Lyu, et al. Efficacy of nystatin for the treatment of oral candidiasis: a systematic review and meta-analysis

[2] No authors listed. Nurs Times. Nystatin

[3] No authors listed. Nurs Times. Nystatin

[4] S Arikan, et al. Nystatin LF (Aronex/Abbott)

[5] V H Witten, et al. Nystatin

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Keywords: Nystatin, Fungicidin; Mycostatin supplier, Antibiotic, inhibitors, activators

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