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NF449 octasodium is a highly potent P2X1 receptor antagonist, with IC50s of 0.28, 0.69, and 120 nM for rP2X1, rP2X1+5, P2X2+3, respectively.
| Molecular Weight | 1505.09 |
| Formula | C41H24N6Na8O29S8 |
| CAS Number | 627034-85-9 |
| Form | Solid |
| Solubility (25°C) | DMSO 9 mg/mL Water 9 mg/mL |
| Storage | -20°C, sealed |
| Related P2 Receptor Products |
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| GW 791343 dihydrochloride
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| MRS 2578
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| PPADS Tetrasodium
PPADS tetrasodium salt is a non-selective P2 purinergic antagonist blocking recombinant P2X1, P2X2, P2X3, P2X5 with IC50 of 1-2.6 μM, native P2Y2-like with IC50 of ~ 0.9 mM, and recombinant P2Y4 receptors with IC50 of ~ 15 mM |
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