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Minodronic acid

Cat. No. M10442

All AbMole products are for research use only, cannot be used for human consumption.

Minodronic acid Structure
Synonym:

YM-529; ONO-5920; YH-529

Size Price Availability Quantity
5mg USD 32  USD32 In stock
10mg USD 50  USD50 In stock
25mg USD 80  USD80 In stock
50mg USD 115  USD115 In stock
100mg USD 160  USD160 In stock
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Quality Control & Documentation
Biological Activity

Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors, Minodronic acid (YM-529) is also a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells.

Chemical Information
Molecular Weight 322.15
Formula C9H12N2O7P2
CAS Number 180064-38-4
Solubility (25°C) Water 3 mg/mL (May need adjust pH)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Makoto Tanaka, et al. J Bone Miner Metab. Minodronic acid induces morphological changes in osteoclasts at bone resorption sites and reaches a level required for antagonism of purinergic P2X2/3 receptors

[2] Jun Iwamoto, et al. Bone. Effect of combined teriparatide and monthly minodronic acid therapy on cancellous bone mass in ovariectomized rats: a bone histomorphometry study

[3] K Sato, et al. Br J Cancer. A third-generation bisphosphonate, minodronic acid (YM529), successfully prevented the growth of bladder cancer in vitro and in vivo

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  Catalog
Abmole Inhibitor Catalog




Keywords: Minodronic acid, YM-529; ONO-5920; YH-529 supplier, P2 Receptor, inhibitors, activators

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