All AbMole products are for research use only, cannot be used for human consumption.
Metformin HCl is a biguanide inhibitor that reduces blood glucose mainly by inhibiting hepatic glycogen production (hepatic gluconeogenesis), while Metformin is a CD47 inhibitor in vitro.
Metabolism. 2023 Jan 7;140:155398.
Metformin coordinates with mesenchymal cells to promote VEGF-mediated angiogenesis in diabetic wound healing through Akt/mTOR activation
Metformin hydrochloride purchased from AbMole
Inflamm Res. 2023 Dec 13.
The immunomodulatory effects of metformin in LPS-induced macrophages: an in vitro study
Metformin hydrochloride purchased from AbMole
Neurosci Lett. 2022 Jul 13;783:136708.
Metformin protects against pericyte apoptosis and promotes neurogenesis through suppressing JNK p38 MAPK signalling activation in ischemia/reperfusion injury
Metformin hydrochloride purchased from AbMole
Patent. CN114686433A 2022 Jul 01.
Patent. CN114686433A
Metformin hydrochloride purchased from AbMole
| Cell Experiment | |
|---|---|
| Cell lines | Keratinocytes and fibroblasts |
| Preparation method | Keratinocytes or fibroblasts were washed and incubated with D/F medium containing 50 % CM or Ctrl for 48 h. Rapamycin (rapa; 1 μM; Abmole, M1768) or MTF (0.03 mM, 0.3 mM, 0.6 mM, 1.0 mM, 2.0 mM, or 3.0 mM; Abmole; M2049) was added before treatment with CM or Ctrl. |
| Concentrations | 0.03 mM, 0.3 mM, 0.6 mM, 1.0 mM, 2.0 mM, or 3.0 mM |
| Incubation time | 48 h |
| Animal Experiment | |
|---|---|
| Animal models | Diabetic wound mice |
| Formulation | MTF was dissolved in drinking water |
| Dosages | 250 mg/kg/day |
| Administration | Oral gavage |
| Molecular Weight | 165.62 |
| Formula | C4H11N5.HCl |
| CAS Number | 1115-70-4 |
| Solubility (25°C) | Water ≥ 30 mg/mL |
| Storage | 2-8°C, protect from light, dry, sealed |
| Related Autophagy Products |
|---|
| Tacrolimus (FK506)
Tacrolimus (FK506, FR900506, Fujimycin, Prograf) is a potent, clinically-useful immunosuppressant in the same molecular class as cyclosporin A and rapamycin. *The compound is unstable in solutions, freshly prepared is recommended |
| Ginkgolide K
Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signaling pathway. |
| Ivermectin (MK-933)
Ivermectin (MK-933) is a positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor and the purinergic P2X4 receptor. Importin α5 inhibitor ivermectin effectively abrogates STAT1-importin α5 interactions. |
| Bergapten
Bergapten is a psoralen that can be photoactivated and is capable of crossing-linking DNA, covalently modifying proteins and lipids, and consequently inhibiting cell replication. |
| Chloroquine diphosphate
Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
