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Jr-ab2-011 is a selective mTORC2 inhibitor with an IC50 value of 0.36 μM. Jr-ab2-011 inhibited mTORC2 activity by blocking the Rictor-MTOR complex (Ki: 0.19 μM). Jr-ab2-011 has anti-glioblastoma multiforme (GBM) activity.
| Molecular Weight | 398.28 |
| Formula | C17H14Cl2FN3OS |
| CAS Number | 2411853-34-2 |
| Solubility (25°C) | DMSO ≥ 40 mg/mL |
| Storage | 4°C, protect from light, dry, sealed |
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