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HG106

Cat. No. M25560

All AbMole products are for research use only, cannot be used for human consumption.

HG106 Structure
Size Price Availability Quantity
5mg USD 170  USD170 In stock
10mg USD 280  USD280 In stock
25mg USD 540  USD540 In stock
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Quality Control & Documentation
Biological Activity

HG106 is a potent SLC7A11 inhibitor, it can enhance ROS generation, ER stress, and lead to ultimately growth arrest specifically in KRAS-mutant lung adenocarcinoma (LUAD).

Chemical Information
Molecular Weight 316.74
Formula C15H13ClN4O2
CAS Number 928712-10-1
Solubility (25°C) DMSO 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Kewen Hu, et al. J Clin Invest. Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma

[2] Kewen Hu, et al. J Clin Invest. Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma

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Keywords: HG106 supplier, ROS, inhibitors, activators

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