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GSK106 

Cat. No. M28778

All AbMole products are for research use only, cannot be used for human consumption.

GSK106  Structure

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Quality Control & Documentation
Biological Activity

GSK106 is an inactive control for the selective PAD4 inhibitors, GSK484 and GSK199.

Chemical Information
Molecular Weight 437.97
Formula C24H28ClN5O
CAS Number 1652591-82-6
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage -20°C, dry, sealed
Related PAD Products
GSK484 hydrochloride

GSK484 hydrochloride is a potent selective reversible inhibitor of protein arginine deiminase PAD4, an enzyme believed to play a role in granulocyte and macrophage development leading to inflammation and immune response, and overexpressed in many tumors.

Cl-amidine hydrochloride

Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively.

GSK199 hydrochloride

GSK199 hydrochloride is a selective PAD4 inhibitor with half-maximum inhibitory concentration (IC50) values, in the absence of calcium, of 200 nM.

GSK-121 Trifluoroacetate

GSK-121 Trifluoroacetate is a selective inhibitor of PAD4.

BB-Cl-Amidine

BB-Cl-Amidine is a peptidylarginine deminase (PAD) inhibitor.

  Catalog
Abmole Inhibitor Catalog




Keywords: GSK106  supplier, PAD, inhibitors, activators

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