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GPP78 (CAY10618) is a potent Nampt inhibitor with an IC50 of 3.0 nM for nicotinamide adenine dinucleotide (NAD) depletion. GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y cells with an IC50 of 3.8 nM by inducing autophagy. GPP78 has anti-cancer and anti-inflammatory effects.
| Molecular Weight | 439.55 |
| Formula | C27H29N5O |
| CAS Number | 1202580-59-3 |
| Form | Liquid |
| Storage | -20°C |
| Related NAMPT Products |
|---|
| STF-118804
STF-118804 is a highly specific NAMPT inhibitor. |
| P7C3
P7C3 is an orally bioavailable and blood-brain barrier penetrant aminopropyl carbazole, with neuroprotective effects. P7C3 exerts its proneurogenic activity by protecting newborn neurons from apoptosis. P7C3 also enhances learning and memory in aged rats. |
| CHS-828
CHS-828 (GMX1778) is a potent and specific inhibitor of NAMPT with IC50 and Kd value of <25 nM and 120 nM, respectively. |
| LSN3154567
LSN3154567 (also known as Nampt-IN-1) is a potent and elective NAMPT inhibitor, inhibits purified NAMPT with an IC50 of 3.1 nM. |
| GNE-617
GNE-617 is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor with IC50 value of 5nM. |
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Products are for research use only. Not for human use. We do not sell to patients.
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