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Gatifloxacin hydrochloride

Cat. No. M19867

All AbMole products are for research use only, cannot be used for human consumption.

Gatifloxacin hydrochloride Structure
Synonym:

AM-1155 hydrochloride; CG5501 hydrochloride; BMS-206584 hydrochloride; PD135432 hydrochloride

Size Price Availability Quantity
50mg USD 60  USD60 In stock
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Quality Control & Documentation
Biological Activity

Gatifloxacin (AM-1155, CG5501, BMS-206584, PD135432) hydrochloride is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases with IC50 of 13.8 μg/ml and 0.109 μg/ml for S. aureus topoisomerase IV and E. coli DNA gyrase, respectively.

Chemical Information
Molecular Weight 411.86
Formula C19H23ClFN3O4
CAS Number 121577-32-0
Solubility (25°C) DMSO 4 mg/mL
Water 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Saravanakumar Arthanari, et al. Artif Cells Nanomed Biotechnol. Preparation and characterization of gatifloxacin-loaded alginate/poly (vinyl alcohol) electrospun nanofibers

[2] Namrata Sharma, et al. Eye Contact Lens. Evaluation of 0.3% gatifloxacin hydrochloride in decontamination of donor corneas

[3] Eun Ju Lee, et al. Bioprocess Biosyst Eng. Studies on the characteristics of drug-loaded gelatin nanoparticles prepared by nanoprecipitation

[4] Joel W Proksch, et al. J Ocul Pharmacol Ther. Ocular pharmacokinetics/pharmacodynamics of besifloxacin, moxifloxacin, and gatifloxacin following topical administration to pigmented rabbits

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Keywords: Gatifloxacin hydrochloride, AM-1155 hydrochloride; CG5501 hydrochloride; BMS-206584 hydrochloride; PD135432 hydrochloride supplier, Topoisomerase, inhibitors, activators

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