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DMP 696 is a selective corticotropin-releasing hormone receptor 1 (CRHR1) antagonist, used for the treatment of anxiety and depression.
| Molecular Weight | 410.3 |
| Formula | C18H21Cl2N5O2 |
| CAS Number | 202578-52-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related CRFR Products |
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| Verucerfont
Verucerfont is a corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50s of ~6.1, >1000 and >1000 nM for CRF1, CRF2, and CRF-BP, respectively. |
| Antalarmin hydrochloride
Antalarmin hydrochloride is a non-peptide CRF1 corticotropin-releasing factor receptor antagonist with a Ki of 1 nM. |
| CP-154526 hydrochloride
CP-154526 hydrochloride is a selective, non-peptide antagonist of corticotropin releasing factor receptors (CRF1) with a Ki of 2.7 nM. CP 154526 hydrochloride shows selective for CRF1 over CRF2 (Ki = >10 μM). |
| CP-376395
CP-376395 is a CRF1-selective antagonist. |
| CRF (bovine) TFA
CRF (bovine) TFA is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM. |
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