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Darexaban

Cat. No. M56687

All AbMole products are for research use only, cannot be used for human consumption.

Darexaban Structure

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Quality Control & Documentation
Biological Activity

Darexaban (YM150) is a potent, selective and orally active factor Xa (FXa) inhibitor with an IC50 of 54.6 nM.

Chemical Information
Molecular Weight 474.55
Formula C27H30N4O4
CAS Number 365462-23-3
Form Solid
Solubility (25°C) DMSO 150 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Related Factor Xa Products
Apixaban

Apixaban is a highly selective, reversible and orally active direct factor Xa inhibitor with an IC50 of 0.22±0.02 µM.

Rivaroxaban

Rivaroxaban (Xarelto, BAY 59-7939) is oral direct factor Xa inhibitor with an IC50 value of 2.1nM.

Betrixaban

Betrixaban is a highly potent, selective, and orally efficacious factor Xa inhibitor with IC50 of 1.2 nM(inhibition of Factor 10a).

Edoxaban Tosylate Monohydrate

Edoxaban tosylate monohydrate is a selective factor Xa inhibitor with Ki of 0.561 nM, >10000-fold selectivity over thrombin and FIXa, and is also an orally bioavailable anticoagulant compound.

BMS-740808

BMS-740808 is a highly potent, selective inhibitor of blood coagulation factor Xa (fXa) with Ki with 0.03 nM.

  Catalog
Abmole Inhibitor Catalog




Keywords: Darexaban supplier, Factor Xa, inhibitors, activators

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