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Corticotropin-releasing factor human (Human CRF) stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary.
| Molecular Weight | 4757.45 |
| CAS Number | 86784-80-7 |
| Solubility (25°C) | Water 25 mg/mL (ultrasonic and adjust pH to 2 with HCl) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] Limor Regev, et al. Corticotropin releasing factor in neuroplasticity
| Related CRFR Products |
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Verucerfont is a corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50s of ~6.1, >1000 and >1000 nM for CRF1, CRF2, and CRF-BP, respectively. |
| Antalarmin hydrochloride
Antalarmin hydrochloride is a non-peptide CRF1 corticotropin-releasing factor receptor antagonist with a Ki of 1 nM. |
| CP-154526 hydrochloride
CP-154526 hydrochloride is a selective, non-peptide antagonist of corticotropin releasing factor receptors (CRF1) with a Ki of 2.7 nM. CP 154526 hydrochloride shows selective for CRF1 over CRF2 (Ki = >10 μM). |
| CP-376395
CP-376395 is a CRF1-selective antagonist. |
| CRF (bovine) TFA
CRF (bovine) TFA is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM. |
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