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Concanavalin A

Cat. No. M9887

All AbMole products are for research use only, cannot be used for human consumption.

Concanavalin A Structure
Size Price Availability Quantity
5mg USD 22  USD22 In stock
10mg USD 33  USD33 In stock
25mg USD 50  USD50 In stock
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Quality Control & Documentation
Biological Activity

Concanavalin A is a protein containing only β-sheets in its structure, and belongs to the legume lectins family. Concanavalin A stimulates acute hepatic inflammation. Concanavalin A has inhibitory effect on hepatocellular carcinoma by inducing autophagy. It can be used to construct dry eye models, as well as autoimmune hepatitis models.

Product Citations
Protocol (for reference only)
Cell Experiment
Cell lines
Preparation method
Concentrations
Incubation time
Animal Experiment
Animal models BALB/c mice
Formulation pyrogen-free PBS
Dosages 15 mg/kg
Administration Intravenous injection
Chemical Information
CAS Number 11028-71-0
Solubility (25°C) Water 5 mg/mL
PBS 5 mg/mL
Storage Powder -20°C, dry, sealed
References

[1] Y-C Lai, et al. Cell Death Dis. Macrophage migration inhibitory factor has a permissive role in concanavalin A-induced cell death of human hepatoma cells through autophagy

[2] Wen-wen Li, et al. Biochem Biophys Res Commun. Concanavalin A: a potential anti-neoplastic agent targeting apoptosis, autophagy and anti-angiogenesis for cancer therapeutics

[3] Huan-Yao Lei, et al. Autophagy. Induction of autophagy by concanavalin A and its application in anti-tumor therapy

[4] Chih-Peng Chang, et al. Hepatology. Concanavalin A induces autophagy in hepatoma cells and has a therapeutic effect in a murine in situ hepatoma model

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