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Ciprofloxacin inhibits topoisomerase IV as a primary topoisomerase target and gyrase as a secondary target. Ciprofloxacin (Bay-09867) (1 mg/L) induces glutathione-S-transferase (GST) activity, in contrast with inhibited GST and Catalase (CAT) of larvae exposed to enrofloxacin. Ciprofloxacin (Bay-09867) (≥10 μg/L) and enrofloxacin are ecotoxic for development, growth, detoxifying, and oxidative stress enzymes in anuran amphibian larvae.
Foodborne Pathog Dis. 2023 Feb;20(2):67-79.
Antibacterial Mechanism of Shikonin Against Vibrio vulnificus and Its Healing Potential on Infected Mice with Full-Thickness Excised Skin
Ciprofloxacin purchased from AbMole
| Molecular Weight | 331.34 |
| Formula | C17H18FN3O3 |
| CAS Number | 85721-33-1 |
| Solubility (25°C) | Soluble in 0.1N HCl ~10mg/mL |
| Storage | 2-8°C, protect from light, sealed |
| Related Topoisomerase Products |
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| Amonafide
Amonafide is a unique ATP-independent Topo II inhibitor that is being studied in the treatment of cancer. |
| Idarubicin
Idarubicin is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells. |
| Dexrazoxane hydrochloride
Dexrazoxane HCl (ICRF-187, ADR-529, DXZ) is an iron chelator that can be used to prevent DOX-induced cardiotoxicity. |
| Irinotecan Hydrochloride Trihydrate
Irinotecan hydrochloride trihydrate is a potent inhibitor of DNA topoisomerase I. |
| Topotecan hydrochloride
Topotecan hydrochloride is a topoisomerase I inhibitor and an apoptosis inducer. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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