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Calmidazolium chloride (R 24571) is a calmodulin antagonist that antagonizes CaM-dependent phosphodiesterase and calmodulin-induced activation of Ca2+-transporting ATPase in erythrocytes with IC50s of 0.15 and 0.35 μM, respectively. it is also used in anticancer studies. It binds CaMK with a Kd value of 3 nM.
| Molecular Weight | 687.7 |
| Formula | C31H23Cl7N2O |
| CAS Number | 57265-65-3 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage | -20°C, dry, sealed |
| Related CaMK Products |
|---|
| KN-62
KN-62 is a selective, cell permeable inhibitor of calcium/calmodulin-dependent kinase II (CaMKII; IC50 = 900 nM). |
| NH125
NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor. |
| KN-92 phosphate
KN-92 is an inactive analog of the CaM kinase II inhibitor KN-93. |
| A23187
Calcimycin (A-23187) is a calcium ionophore that induces Ca2+-dependent cell death by increasing intracellular calcium concentration. |
| KN-92
KN-92 is an inactive analog of the CaM kinase II inhibitor KN-93. |
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Products are for research use only. Not for human use. We do not sell to patients.
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