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Calhex 231 is a negative allosteric modulator of the calcium sensing receptor (CaSR). Calhex 231 blocks increases in [3H]inositol phosphate levels elicited by wild-type hCasR activation (IC50= 0.39 μM in transiently transfected HEK293 cells).
| Molecular Weight | 406.95 |
| Formula | C25H27ClN2O |
| CAS Number | 652973-93-8 |
| Solubility (25°C) | DMSO 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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