Free shipping on all orders over $ 500

Brivudine

Cat. No. M7515

All AbMole products are for research use only, cannot be used for human consumption.

Brivudine Structure
Synonym:

BVDU; Bromovinyldeoxyuridine

Size Price Availability Quantity
10mM*1mL in DMSO USD 41  USD41 In stock
10mg USD 30  USD30 In stock
25mg USD 40  USD40 In stock
50mg USD 55  USD55 In stock
100mg USD 73  USD73 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Brivudine is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. It is incorporated into the viral DNA and blocks the action of DNA polymerases, thus inhibiting viral replication.

Product Citations
Chemical Information
Molecular Weight 333.14
Formula C11H13BrN2O5
CAS Number 69304-47-8
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Hew K, et al. PLoS One. Structure of the Varicella Zoster Virus Thymidylate Synthase Establishes Functional and Structural Similarities as the Human Enzyme and Potentiates Itself as a Target of Brivudine.

[2] Gonen I, et al. J Chemother. Brivudin induced delirium: a case report.

Related DNA/RNA Synthesis Products
Clofarabine

Clofarabine inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.

Gemcitabine Hydrochloride

Gemcitabine (Gemzar, LY188011) inhibits DNA synthesis with an IC50 of 0.06 µM.

Nelarabine

Nelarabine is a novel purine antimetabolite antineoplastic agent.

Mizoribine

Mizoribine (Bredinin) is an imidazole nucleoside and an immunosuppressive agent with an IC50 of approximately 100 μM. Mizoribine inhibits replication of SARS-CoV with IC50s of 3.5 μg/mL and 16 μg/mL for SARS-CoV Frankfurt-1 and SARS-CoV HKU39849, respectively.

Capecitabine

Capecitabine is an orally-administered chemotherapeutic agent. Capecitabine is a precursor, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. Capecitabine may inhibit cytochrome CYP2C9 enzyme, and therefore increase levels of substrates such as phenytoin and other substrates of CYP2C9.

  Catalog
Abmole Inhibitor Catalog




Keywords: Brivudine, BVDU; Bromovinyldeoxyuridine supplier, DNA/RNA Synthesis, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.