All AbMole products are for research use only, cannot be used for human consumption.
Benzocaine is the ethyl ester of p-aminobenzoic acid (PABA), it is a local anesthetic commonly used for the research of topical pain reliever or in cough drops. Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel, with an IC50 of 0.8 mM tested with a potential of +30 mV.
Benzocaine is topically applied to the following species: dogs, domestic shorthair cats, Long-Evans rats, Sprague-Dawley rats, ferrets, rhesus monkeys, cynomolgus monkeys, owl monkeys, New Zealand White rabbits, miniature pigs, ICR mice, C3H mice, and C57BL/10SnJ mice.
| Molecular Weight | 165.19 |
| Formula | C9H11NO2 |
| CAS Number | 94-09-7 |
| Solubility (25°C) | DMSO 85 mg/mL |
| Storage | 4°C, protect from light |
[1] Syeda Khair-Ul-Bariyah, et al. Benzocaine: Review on a Drug with Unfold Potential
[2] Subrat Khanal, et al. Benzocaine-Associated Methemoglobinemia
[3] Michael R Kaufman, et al. Benzocaine-Induced Methemoglobinemia
[4] Jodi Lehr, et al. Benzocaine-induced methemoglobinemia in the pediatric population
| Related Animal experimental anesthetics Products |
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Articaine hydrochloride is a dental local anesthetic which contains an additional ester group that is metabolized by estearases in blood and tissue. Articaine hydrochloride ameliorates LPS-induced acute kidney injury via inhibition of NF-ĸB activation and the NLRP3 inflammasome pathway. |
| Butacaine
Butacaine is a reversible nerve conduction blocker. Butacaine acts on the nervous system and nerve fibers, can cause both sensory and motor paralysis. Butacaine inhibits mouse heart MAO (type B) and rat heart MAO (type A) with IC50 of 62 μM and 400 μM, respectively. |
| Dibucaine hydrochloride
Dibucaine (Cinchocaine) hydrochloride is a sodium channel inhibitor. Dibucaine hydrochloride is a potent SChE inhibitor. Dibucaine hydrochloride is a local anesthetics. |
| Levobupivacaine hydrochloride
Levobupivacaine hydrochloride is a long-acting amide local anaesthetic. Levobupivacaine hydrochloride exerts anaesthetic and analgesic effects through reversible blockade of neuronal sodium channel. |
| Mepivacaine hydrochloride
Mepivacaine is a tertiary amine used as a local anesthetic. |
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