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Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R. Anakinra is the first biological agent to block the pro-inflammatory effects. In vivo, combined Etanercept (5 mg/kg, ip) and Anakinra (100 mg/kg, ip. daily for 7 days) substantially improves marginal mass human islet engraftment in immunodeficient mice. Anakinra enhances tumor growth inhibition in mice receiving peptide vaccination and β-(1-3),(1-6)-D-glucan.
Cell Biosci. 2022 Jun 17;12(1):90.
IL-1R/C3aR signaling regulates synaptic pruning in the prefrontal cortex of depression
Anakinra purchased from AbMole
| Molecular Weight | 509.56 |
| Formula | C20H23N5O7S2 |
| CAS Number | 143090-92-0 |
| Storage | 2-8°C, do not freeze |
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Products are for research use only. Not for human use. We do not sell to patients.
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