All AbMole products are for research use only, cannot be used for human consumption.
4E1RCat is a dual inhibitor of eIF4E:eIF4G and eIF4E:4E-BP1 interaction, and inhibits the binding of eIF4G to eIF4E with IC50 of 3.2 μM.
| Molecular Weight | 478.45 |
| Formula | C28H18N2O6 |
| CAS Number | 328998-25-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 80 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[5] Nicholas Arnold, et al. Regulation of cardiac expression of the diabetic marker microRNA miR-29
| Related Eukaryotic Initiation Factor Products |
|---|
| 4EGI-1
4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor by binding to eIF4E with KD of 25 μM. |
| SBI-0640756
SBI-0640756 is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex. |
| Zotatifin
Zotatifin is a first-in-class, sequentially selective inhibitor of RNA helicase eIF4A1. |
| GCN2iB
GCN2iB is an ATP-competitive inhibitor of a serine/threonine-protein kinase general control nonderepressible 2 (GCN2), with an IC50 of 2.4 nM. |
| GCN2-IN-1
GCN2-IN-1 (A-92) is a potent general control nonderepressible 2 kinase (GCN2) inhibitor with an IC50 of <0.3 μM in the enzyme assay and an IC50 of 0.3-3 μM in the cell assay. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
