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2-Hydroxypropyl-β-cyclodextrin

Cat. No. M4893

All AbMole products are for research use only, cannot be used for human consumption.

2-Hydroxypropyl-β-cyclodextrin Structure
Synonym:

Hydroxypropyl betadex; Hydroxypropyl-β-cyclodextrin; HP-β-CD

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
500mg USD 30  USD30 In stock
1g USD 40  USD40 In stock
5g USD 80  USD80 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

2-Hydroxypropyl-β-cyclodextrin functions by forming an inclusion complex with the compound being administered for easier diffusion across biological membranes, and its popularity can be attributed to its large 7 glucose unit cavity size. Some advantageous effects are reduction of negative effects, increased aqueous solubility and increased stability.

Product Citations
Chemical Information
Molecular Weight 1541.54
Formula C63H12O42
CAS Number 128446-35-5
Solubility (25°C) Water 100 mg/mL
DMSO 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Haocheng Lu, et.al. Circulation. Cyclodextrin Prevents Abdominal Aortic Aneurysm via Activation of Vascular Smooth Muscle Cell Transcription Factor EB

[2] Frijlink HW,et.al. Pharm Res. The effects of cyclodextrins on the disposition of intravenously injected drugs in the rat.

Related Solvents & Excipients Products
SBE-β-CD

SBE-β-CD (Sulfobutylether beta-cyclodextrin) is a unique reproducible mixture of polyanionic β-cyclodextrin derivatives in which a sodium sulfonate salt is tethered to the lipophilic cyclodextrin cavity by a butyl ether group, or sulfobutylether (SBE).

Hydroxyethyl cellulose

Hydroxyethyl cellulose is a non-ionic, modified cellulose polymer used as a thickening agent.

Hydroxypropyl methyl cellulose (HPMC)

Hydroxypropyl methyl cellulose (HPMC) is a water-soluble hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices.

Methyl α-D-glucopyranoside

Methyl α-D-glucopyranoside can be used in a study to investigate saccharide-mediated protection of chaotropic-induced deactivation of concanavalin A.

MES, free acid

MES, free acid is a commonly used buffer. MES (2-Morpholinoethanesulphonic acid) is a buffering agent in biology and biochemistry, the buffer capacity ranging pH 5.5-7.0. MES is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments.

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Keywords: 2-Hydroxypropyl-β-cyclodextrin, Hydroxypropyl betadex; Hydroxypropyl-β-cyclodextrin; HP-β-CD supplier, Solvents & Excipients, inhibitors, activators

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