| Cat.No. | Name | Information |
|---|---|---|
| M4614 | Orientin | Orientin |
| M9358 | ITE | ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), which directly binding to AHR with a Ki of 3 nM. |
| M10093 | α-Galactosyl Ceramide | α-Galactosyl Ceramide (KRN 7000, alpha-GalCer) is a potent NKT cell stimulator and selective CD1d ligand. α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. |
| M1831 | Cyclosporine A | Cyclosporine A (CsA，Cyclosporin A) is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. Cyclosporine A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation. |
| M20413 | 4-Biphenylacetic acid | 4-Biphenylacetic acid (BPA) is a potential non-steroidal anti-inflammatory agent and forms solid inclusion complex with β-cyclodextrin. Its interaction with quinolone antibacterial agents can induce functional blockade of the γ-aminobutyric acid receptors. |
| M25413 | Fucoxanthin | Fucoxanthin is a carotenoid that occurs naturally in certain algae with anti-obesity, anti-oxidant, anti-diabetic, anticancer and anti-inflammatory activities. |
| M55368 | 2-Hydroxy Fluorene | 2-Hydroxy Fluorene (2-FLU) has a wide range of applications in life science related research. 2-FLU can increase the expression of psoriasis-related inflammatory factors in HaCaT cells. |
| M55040 | Litifilimab | Litifilimab is a humanized IgG1-κ antibody targeting to C-type lectin domain family 4 member C (CLEC4C). |
| M9052 | ST2825 | ST-2825 is MyD88 inhibitor. |
| M3297 | Meloxicam | Meloxicam (Mobic) is a nonsteroidal anti-inflammatory agent with analgesic and fever reducer effects. |
| M4616 | Cucurbitacin B | Cucurbitacin B is a natural compound with anticancer activity. Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest. |
| M4389 | Carnosol | Carnosol is a phenolic diterpene with antioxidant and anticarcinogenic activities. |
| M4274 | Edpetiline | Edpetiline is a major alkaloid from P. Eduardi. Edpetiline has significant anti-inflammatory effects. |
| M4139 | Salvianolic-acid-A | Salvianolic-acid-A |
| M3980 | Dipsacoside B | Dipsacoside B is extracted from Lonicara confusa DC. dried buds and flowers. Dipsacoside B showes strong antimicrobial activity. |
| M3634 | TAPI-1 | TAPI-1 is an ADAM17/TACE inhibitor that blocks shedding of cytokine receptors with IC50 value of 8.09 microM. |
| M3468 | Methylprednisolone | Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. |
| M3416 | Mycophenolic acid | Mycophenolic acid is an immunosuppressant agent used to prevent rejection in organ transplantation. |
| M3297 | Meloxicam | Meloxicam (Mobic) is a nonsteroidal anti-inflammatory agent with analgesic and fever reducer effects. |
| M2221 | Pimecrolimus | Pimecrolimus is an immunomodulating agent used in the treatment of atopic dermatitis. |
| M1803 | Laquinimod | Laquinimod (ABR-215062) is a new orally active immunoregulator effectively inhibits development and relapses of experimental autoimmune encephalomyelitis. |
| M1616 | Daratumumab | Daratumumab (Daratumumab) is a first-in-class, specific anti-CD38 monoclonal antibody (IgG1). (for human or immunodeficient mice). |
| M1539 | Omalizumab | Omalizumab is a recombinant DNA-derived humanized IgG1k monoclonal antibody that specifically binds to free human immunoglobulin E (IgE) and to membrane-bound form of IgE (mIgE). |
| M58996 | Rolistobart | Rolistobart is a humanized immunoglobulin G4-kappa, anti-LILRB4/CD85k monoclonal antibody. |
| M55021 | MK-4830 | MK-4830 is a novel, first-in-class human IgG4 monoclonal antibody targeting the myeloid-specific ILT4 (immunoglobulin-like transcript 4) receptor. MK-4830 catalyzes reprogramming of tumour-associated macrophages, relieving myelosuppression and enhancing T cell function. |
| M54836 | Lobenzarit | Lobenzarit is an immunomodulator, possesses anti-oxidative. |
| M54803 | ORIC-533 | ORIC-533 is a highly potent and selective, orally bioavailable, Best-in-Class small molecule inhibitor of CD73, an enzyme expressed by various cell types, including immune cells and which catalyzes the generation of adenosine from adenosine monophosphate (AMP). |
| M50650 | Onilcamotide | Onilcamotide is a C-terminal peptide of RhoC protein. Onilcamotide is a cancer vaccine and has potential immunomodulating and antineoplastic activities. |
| M41959 | BK50164 | BK50164 is a potent CD73 inhibitor with an IC50 value of 13.089 µM. |
| M41958 | CCT374705 | CCT374705 is an orally active BCL6 inhibitor with potent antiproliferative effects in vitro. |
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