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Metabolite/Endogenous Metabolite Metabolite/Endogenous Metabolite

Inhibitor

Cat.No.  Name Information
M31283 Glucose oxidase Glucose oxidase (GOD) is an oxidoreductase enzyme that inhibits the proliferation of cancer cells by reacting with intracellular oxygen (O2) and β-D-glucose to produce hydrogen peroxide (H2O2) and gluconic acid, thereby cutting off the source of nutrients for cancer cells.
M18309 p-Hydroxy-cinnamic acid p-Hydroxy-cinnamic acid inhibits platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively.
M10346 L-Glutamic acid L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).
M10168 L-Lactic acid L-Lactic acid is an organic acid, which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.
M9953 Taurocholic acid Taurocholic acid (N-Choloyltaurine) is a bile acid, which can be used in the emulsification of fats.
M9076 NADPH tetrasodium salt NADPH tetrasodium salt is a cofactor, used to donate electrons and a hydrogens to reactions catalyzed by some enzymes. NADPH tetrasodium salt functions as an important cofactor in a variety of metabolic and biosynthetic pathways. NADPH tetrasodium salt plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication.
M6687 Docosahexaenoic acid (Oil) Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. Docosahexaenoic acid is a RXR agonist.
M59292 PMSG PMSG (Pregnant mare serum gonadotropin) is a gonadotropin used to promote follicular development and ovulation in animals. PMSG exerts its regulatory effects by stimulating changes in blood hormones, gonadotropins, and cytoplasmic estradiol receptors in the anterior pituitary and hypothalamus.
M59273 2-Deoxy-D-galactose 2-Deoxy-D-galactose is a glucose analog that inhibits glycolysis to inhibits tumor growth. 2-Deoxy-d-galactose hinders glycoprotein fucosylation in vivo.
M59257 3-Methyluridine 3-Methyluridine is a methylated nucleotide present in ribosomal RNA (rRNA), mainly targeting specific base sites of RNA molecules such as 23S rRNA. 3-Methyluridine can introduce a methyl group at the N3 position of uracil, affecting the secondary structure stability and base pairing ability of RNA, and regulating ribosome function.
M59179 1a,1b-dihomo Prostaglandin F2α 1a,1b-dihomo Prostaglandin F2α (1a,1b-dihomo PGF2α) is a hypothetical product of adrenic acid in the COX pathway.
M59161 Dihydrothymine Dihydrothymine (5,6-Dihydro-5-methyluracil) is an intermediate breakdown product of thymine, comes from animal or plants.
M59121 Lithium acetoacetate Lithium acetoacetate (Acetoacetic acid lithium) is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Lithium acetoacetate induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes.
M59096 Gentisuric Acid Gentisuric Acid is a metabolite of Aspirin, it is a substrate of α-amidating monooxygenase (PAM). Gentisuric acid prevents DNA-damage by Mitomycin C.
M59095 5α-Dihydroprogesterone 5α-Dihydroprogesterone (5a-Pregnane-3,20-dione) is the endogenous progesterone metabolite. 5α-Dihydroprogesterone (5a-Pregnane-3,20-dione) decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerizes F-actin in MCF-7 breast cancer cells.
M59086 Adenosine 2',3'-cyclic phosphate sodium Adenosine 2',3'-cyclic phosphate sodium serves as an extracellular source of adenosine. The release of extracellular 2′,3′-cAMP occurs in response to injury. 2′,3′-cAMP may be used to study the distribution and specificity of its degrading enzymes in the context of unique biological activities. 2′,3′-cAMP may also be used to study apoptosis induced at the level of mitochondrial permeability transition pores. 2′,3′-cAMP is converted into 2′-AMP and 3′-AMP which inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors.
M59073 6α-Hydroxy Paclitaxel 6α-Hydroxy Paclitaxel is a primary metabolite of Paclitaxel. 6α-Hydroxy Paclitaxel (6-Hydroxytaxol) retains a time-dependent effect on organic anion-transporting polypeptides 1B1/SLCO1B1 (OATP1B1) with similar inhibition potency to Paclitaxel, whereas it no longer showed time-dependent inhibition of OATP1B3.
M59035 Casein (from bovine milk) Casein is a phosphorus-containing complex protein with α-casein and β-casein as its main components. Casein is an orally active phosphoprotein that can be separated into various electrophoretic components, such as α2-Casein, κ-Casein, β-casein, and γ-casein. Casein can be used in biochemical research, to formulate biological culture media, and as a thickener, emulsifier and stabiliser.
M59027 Palmitic acid-13C16 Palmitic acid-13C16 is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants.
M59016 Methionine sulfoximine Methionine sulfoximine (2-Amino-4-(S-methylsulfonimidoyl)butanoic acid) is an irreversible inhibitor of glutamine synthetase. Methionine sulfoximine is able to affect the metabolism of glutamate and glutamine.




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