| Cat.No. | Name | Information |
|---|---|---|
| M59051 | 8-Azido-3,6-dioxaoctanoic Acid Cyclohexylamine Salt | 8-Azido-3,6-dioxaoctanoic Acid Cyclohexylamine Salt is a azido-modified PEG2 acid, can be used as a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. |
| M58963 | DOTA-NHS-ester | DOTA-NHS-ester is a linker for affibody molecules and is applied in small animals PET. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for the detection of tumors. |
| M58397 | Sulfo-LC-SPDP sodium | Sulfo-LC-SPDP sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| M58138 | DBCO-Maleimide | DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. |
| M55714 | Mal-PEG4-Val-Cit-PAB-PNP | Mal-PEG4-Val-Cit-PAB-PNP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| M55709 | Fmoc-NH-ethyl-SS-propionic acid | Fmoc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| M54791 | DBCO-acid | DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester, and agent-linker conjugates DBCO-PEG-MMAE. |
| M49828 | Propargyl-C1-NHS ester | Propargyl-C1-NHS ester is a non-degradable linker that can be used to synthesize antibody coupled active molecules (ADCs). In addition, Propargyl-C1-NHS ester is a click chemistry reagent. It contains an Alkyne moiety and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an Azide moiety. |
| M45209 | Maleimido-mono-amide-DOTA | Maleimido-mono-amide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| M41004 | MC-VC-PAB-NH2 TFA | MC-VC-PAB-NH2 TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| M40546 | Trastuzumab Emtansine | Trastuzumab Emtansine is a HER2-targeting antibody-drug concatenation (ADC) that can be used in studies related to HER2-positive metastatic breast cancer. |
| M40544 | Mirvetuximab soravtansine | Mirvetuximab soravtansine is an antibody-drug concatenation (ADC) containing a folate receptor alpha (frα)-conjugated antibody, a cleavable junction, and the medenosine alkaloid DM4, a potent microtubulin-targeting agent, that can be used in studies related to platinum-resistant epithelial ovarian cancer (EOC). |
| M40540 | Sacituzumab govitecan | Sacituzumab govitecan is an antibody-drug concatenation (ADC) containing a humanized anti-trophoblast cell surface antigen 2 (TROP-2) antibody as well as the topoisomerase I inhibitor SN-38。It delivers high concentrations of SN-38 to tumors and can be used in studies related to triple-negative breast cancer. |
| M30969 | Mal-amido-PEG2-NHS ester | Mal-amido-PEG2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. |
| M13455 | Fmoc-Phe-Lys(Boc)-PAB-PNP TFA | Fmoc-Phe-Lys(Boc)-PAB-PNP TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| M13454 | DSP Crosslinker | DSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs). |
| M13453 | DBCO-NHS ester | DBCO-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| M13342 | DSG Crosslinker | DSG Crosslinker is a cleavable ADC linker that can be used to synthesize antibody-conjugated drugs (ADCs). |
| M10414 | Fmoc-3VVD-OH | Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| M10413 | Boc-Val-Cit-PAB | Boc-Val-Cit-PAB is a cleavable ADC linker used in making antibody-drug conjugates (ADCs). |
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