| Cat.No. | Name | Information |
|---|---|---|
| M59390 | (E)-N-(p-Amylcinnamoyl)anthranilic acid | N-(p-Amylcinnamoyl)anthranilic acid is a broad spectrum PLA2 inhibitor and TRP channel blocker. N-(p-Amylcinnamoyl)anthranilic acid (ACA) functions as a broad spectrum phospholipase A2 inhibitor and blocks transient receptor potential (TRP) channels. It inhibits calcium activated chloride current in cardiac ventricular myocytes. N-(p-Amylcinnamoyl)anthranilic acid has been used as a transient receptor potential cation channel subfamily M member 2 (TRPM2) inhibitor, in studying its role in regulating the production of reactive oxygen species (ROS). |
| M59388 | Carboxylesterase (from porcine liver) | Carboxylesterase, also known as carboxyl ester hydrolase is a member of the hydrolase superfamily of enzymes. Pig liver esterase catalyzes enantioselective conversion of an ester to a carboxylic acid. The molecular weight is found to be 168 kDa. It is a serine enzyme with two active sites on each molecule, which dissociates into active half-molecules in the presence of dilute acid or concentrated salts. |
| M59387 | Orotidine | Orotidine, a nucleotide, is an intermediate in pyrimidine nucleotide biosynthesis in RNA and DNA. Orotidine is mainly found in bacteria, fungi and plants. |
| M59386 | 2'-F-Bz-A | 2'-F-Bz-A (N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides. |
| M59385 | Tiazofurin | Tiazofurin (NSC 286193) is a synthetic nucleoside analogue with antineoplastic activity. |
| M59384 | Orotidine 5′-monophosphate trisodium | Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5'-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms. |
| M59382 | Tadnersen | Tadnersen (BIIB078), an antisense oligonucleotide (ASO), selectively targets C9ORF72 transcript variants 1 and 3 that carry the expansion. |
| M59381 | Trabedersen sodium | Trabedersen sodium is an antisense oligodeoxynucleotide that specifically inhibits TGF-β2 (TGF-beta/Smad). |
| M59380 | ODN 1668 | ODN 1668, a class B CpG ODN (oligodeoxynucleotide), is a TLR-9 agonist. ODN 1668 has strong immune regulatory properties, can enhance the level of antibody IgG2 subtype, promote the immune response of T cells and B cells, and can be used in the study of vaccine adjuvants. |
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