All AbMole products are for research use only, cannot be used for human consumption.
Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research.
| Molecular Weight | 454.6 |
| CAS Number | 52-53-9 |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage | 2-8°C, protect from light |
[1] D M Krikler. Verapamil in arrhythmia
[3] N X Nguyen, et al. Verapamil and ventricular tachyarrhythmias
[4] Jasmine L Gowarty, et al. Verapamil as a culprit of palbociclib toxicity
| Best-selling Calcium Channel Products |
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| Ionomycin
Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
| Ionomycin (Calcium salt)
Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
| (R)-(+)-BAY K 8644
(R)-(+)-BAY K 8644 is a calcium channel inhibitor, inhibits Ba2+ currents (IBa) with IC50 of 975 nM. |
| Thapsigargin
Thapsigargin is an endoplasmic reticulum (ER) stress inducer, it is also an inhibitor of microsomal Ca2+-ATPase. |
| Other Calcium Channel Products |
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| KB-R7943 mesylate
KB-R7943 mesylate is a potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0.7 mM). |
| Cilnidipine
Cilnidipine is a dual L- and N-type calcium channel blocker that displays antihypertensive, sympatholytic and neuroprotective activity. |
| Azelnidipine
Azelnidipine is a novel dihydropyridine derivative, a L-type calcium channel blocker, and an antihypertensive. Azelnidipine inhibits the intracellular calcium ion flow and lower blood pressure by selectively blocking L-type calcium channel on the membrane of vascular smooth muscle. Azelnidipine inhibits esophageal squamous cell carcinoma proliferation by targeting MEK1/2. Azelnidipine also has anti-inflammatory, antioxidant and neuroprotective effects. |
| Catharanthine
Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM |
| Cinepazide maleate
Cinepazide maleate is a maleate salt form of cinepazide which is a vasodilator. |
| Lomerizine dihydrochloride
Lomerizine dihydrochloride is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
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