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GlcNAcstatin is a selective O-GlcNAcase (OGA) inhibitor with Ki of 4.6 pM.
| Molecular Weight | 373.45 |
| Formula | C20H27N3O4 |
| CAS Number | 922163-64-2 |
| Solubility (25°C) | DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Best-selling OGA/OGT Products |
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| Other OGA/OGT Products |
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| Thiamet G
Thiamet G is a potent, selective O-GlcNAcase (OGA) inhibitor with Ki of 21 nM, while exhibiting 37,000-fold selectivity over human lysosomal –hexosaminidase. |
| OSMI-1
OSMI-1 is a cell permeable inhibitor of OGT (O-GlcNAc transferase) with an IC50 value of 2.7 μM. |
| OSMI-4
OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor, with an EC50 of 3 μM in cells. |
| PG34
PG34 is a weak inhibitor of O-GlcNAc transferase (OGT), with an IC50 value of 68 μM. PG34 demonstrated poor in vitro inhibitory activity against OGT and did not reduce global O-GlcNAcylation in cells. It affected cell viability similarly to OSMI-1. |
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