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PROTAC Linker PROTAC Linker

Cat.No.  Name Information
M9791 5-Ethynyl-2'-deoxyuridine 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
M124548 Sulfo-NHS-Acetate Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
M124547 Methoxypolyethylene glycols (MW2000) Methoxypolyethylene glycols (mPEG) is a PROTAC linker and belongs to the PEG class. It can be used to synthesize PROTAC molecules.
M66466 Amino-PEG3-C2-Azido Azido-PEG3-Amine is a biochemically synthesised linker commonly used in bioconjugation; it can be employed in the synthesis of bioactive molecules and delivery systems, and has certain applications in the synthesis of various targeted drug delivery systems. Amino-PEG3-C2-Azido is a PEG-based PROTAC linker containing an azide group, which can undergo a copper-catalysed azide-alkyne cycloaddition (CuAAc) reaction with molecules containing an alkyne group. It can also undergo a ring-strain-driven acetylene-azide cycloaddition (SPAAC) reaction with molecules containing DBCO or BCN groups.
M66293 Ac4ManNAz Ac4ManNAz is an azide-containing metabolic glycoprotein labeling reagent that selectively modifies proteins. Ac4ManNAz can be taken up by cells. Ac4ManNAz is commonly used for cell labeling, tracking and proteomic analysis. Ac4ManNAz contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups.
M59429 Alkynyl myristic acid Alkynyl myristic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
M59427 Biotin-PEG2-Mal Biotin-PEG2-Mal is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
M59187 DBCO-PEG4-NHS ester DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
M58966 Azido-PEG2-CH2COOH Azido-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG2-CH2COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups.
M58639 Propargyl-PEG1-acid Propargyl-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-CRBN PROTACs. BTK-CRBN PROTACs act as stoichiometric degraders, resulting in degradation of BTK protein. Degradation of BTK is a result of cereblon E3 ligases family recruitment. Propargyl-PEG1-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
M55356 Bis-PEG2-acid Bis-PEG2-acid (COOH-PEG1-COOH) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
M49797 Methoxypolyethylene glycols (MW5000) Methoxypolyethylene glycols (mPEG) is a PROTAC linker and belongs to the PEG class. It can be used to synthesize PROTAC molecules.
M43843 tert-butyl 4-(3,3-difluoropiperidin-4-yl)piperazine-1-carboxylate tert-butyl 4-(3,3-difluoropiperidin-4-yl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
M43842 Tert-butyl 4-((1-((benzyloxy)carbonyl)piperidin-4-yl)methyl)piperazine-1-carboxylate Tert-butyl 4-((1-((benzyloxy)carbonyl)piperidin-4-yl)methyl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
M43841 Tert-butyl 4-(piperidin-4-ylmethyl)piperazine-1-carboxylate Tert-butyl 4-(piperidin-4-ylmethyl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
M39843 Biotin-PEG3-azide Biotin-PEG3-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
M30988 Alkynyl Palmitic Acid Alkynyl Palmitic Acid (Alk-C16) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
M21359 DSPE-PEG-Biotin (MW 2000) DSPE-PEG-Biotin (MW 2000) is a PROTAC linker, which belongs to the PEG class. It can be used to synthesize PROTAC molecules.
M14868 L-Azidohomoalanine hydrochloride L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
M10416 Ac4ManNAz (80% α isomer) Ac4ManNAz is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Ac4ManNAz can be used to selectively modify proteins. Ac4ManNAz can be used in cell labeling, tracking and proteomic analysis. Ac4ManNAz is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups.




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