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Peptides

Cat.No.  Name Information
M58140 HwTx-IV Huwentoxin-IV (HwTx-IV) is a 35-residue neurotoxin peptide with potential application as a novel analgesic. Huwentoxin-IV, a component of tarantula venom, potently blocks sodium channels and is an attractive scaffold for engineering a Nav1.7-selective molecule.
M51229 Gastrin I (human) (sulfated) Gastrin I (human) (sulfated) is a polypeptide that can be found by peptide screening.
M31340 Peceleganan acetate Peceleganan (antimicrobial peptide PL-5) is a chemically synthesized, alpha-helical antimicrobial peptide containing 26 amino acid residues.
M10576 Gramicidin S Gramicidin S is a cyclic peptide antibiotic produced by Bacillus brevis var. Gause-Brazhnikova. Gramicidin S exerts antibacterial activity by destroying membrane integrity and interfering with membrane protein function. Gramicidin S also inhibits ion channels, with IC50s of 41 μM, 24 μM, and 3 μM for Na+/K+-ATPase, tobacco leaf plasma membrane Mg2+/K+-ATPase, and rat heart plasma membrane Ca2+-ATPase, respectively.
M10249 Teduglutide Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue used for the treatment of short-bowel syndrome.
M10246 Bulevirtide Bulevirtide is a first-in-class virion entry inhibitor which blocks the hepatic sodium/taurocholate cotransporting polypeptide (NTCP) receptor.
M10203 ACE-031 ACE-031 (Myostatin inhibitory peptide 7) is a fusion protein of activin receptor type IIB and IgG1-Fc, which binds myostatin and related ligands.
M10196 RADA16 RADA16 (self-assembling short peptide RADA16) offers advantages including high water content, structural stability, excellent biocompatibility, and non-toxic degradation products. It is suitable for research in biomedical fields such as three-dimensional cell culture, tissue repair, rapid haemostasis, and controlled release of compounds or proteins.
M10097 Apelin-13 TFA Apelin-13 is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC 50 value of 0.37 nM.
M10039 GsMTx4 GsMTx4 is a spider venom peptide that selectively inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families.
M9771 TRAP-6 TRAP-6 (Thrombin Receptor Activator Peptide 6) is a peptide fragment (residues 42-47) of protease-activated receptor 1 (PAR1) that acts as a PAR1 agonist.
M9316 Ceruletide Ceruletide is a biologically active decapeptide isolated from the skin of the Australian frog Hyla caerulea, acts as a cholecystokinin receptor agonist.
M9137 Elamipretide TFA Elamipretide TFA, also known as MTP-131, is a cardiolipin peroxidase inhibitor and mitochondria-targeted peptide.
M6240 Angiotensin II human Angiotensin II human is converted by Angiotensin I through removal of two C-terminal residues by the enzyme angiotensin-converting enzyme (ACE). Angiotensin II is mediated by AT1 and AT2 receptors, which are seven transmembrane glycoproteins with 30% sequence similarity. Keep away from light and prepare for use now.
M5735 Leuprolide Acetate Leuprolide acetate is a GnRH analog; leuprolide acetate acts as an agonist at pituitary GnRH receptors.
M2007 Romidepsin (FK228) Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a structurally unique, potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.*The compound is unstable in solutions, freshly prepared is recommended
M1831 Cyclosporine A Cyclosporine A (CsA,Cyclosporin A) is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. Cyclosporine A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation.
M1261 NFAT Inhibitor-1 (VIVIT peptide) NFAT Inhibitor-1 (VIVIT peptide) is a cell-permeable peptide inhibitor of nuclear factor of activated Tcells (NFAT), it is superior at inhibiting calcineurin-mediated dephosphorylation of NFAT1, NFAT2, and NFAT4 in cell extracts.
M124481 T-22 T-22 is a novel anti-HIV synthetic peptide, which had extremely high anti-HIV activity. Its 50% inhibitory concentration (EC50) was 0.008 micrograms/ml, while its 50% cytotoxic concentration (CC50) was 54 micrograms/ml.
M124469 D-GsMTx4 D-GsMTx4 is the D enantiomer of GsMTx4. D-GsMTx4 inhibits the mechanosensitive ion channel Piezo2. D-GsMTx4 inhibits mTOR and PI3K-Akt signaling pathways. D-GsMTx4 inhibits [Ca2+]i elevation.

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